Anti-CES3 antibody (447-497 aa) (STJ193653)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human EST3 at the amino acid range 447-497
General Information
| Short Description | Rabbit polyclonal anti-Carboxylesterase 3 (447-497 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CES3 |
| Gene ID | 23491 |
| Uniprot ID | EST3_HUMAN |
| Immunogen | Synthesized peptide derived from the human EST3 at the amino acid range 447-497 |
| Immunogen Region | 447-497 aa |
| Specificity | This antibody detects endogenous levels of EST3 at Human |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-4-(1-piperidino)-1-piperidino-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics. |
| Protein Name | Carboxylesterase 3Liver Carboxylesterase 31 Homolog |
| Database Links | Reactome: R-HSA-211945Reactome: R-HSA-8964038 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Carboxylesterase 3 antibodyAnti-Liver Carboxylesterase 31 Homolog antibodyAnti-CES3 antibodyAnti-UNQ869 antibodyAnti-PRO1887 antibody |
Information sourced from Uniprot.org