| Post Translational Modifications | Phosphorylated by MAPK1 and CDK2. |
| Function | Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation.represses CDK2 activation by inhibiting its interaction with cyclin E and A. Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes. |
| Protein Name | Cyclin-Dependent Kinase 2-Associated Protein 2Cdk2-Associated Protein 2Doc-1-Related ProteinDoc-1r |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusAccumulates In Immature Oocytes In The NucleusDuring The First Meiotic DivisionAccumulates In The Cytoplasm And Localizes In Dots In The Vicinity Of The Chromosomes In A Region Enriched In Microtubules |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase 2-Associated Protein 2 antibodyAnti-Cdk2-Associated Protein 2 antibodyAnti-Doc-1-Related Protein antibodyAnti-Doc-1r antibodyAnti-CDK2AP2 antibodyAnti-DOC1R antibody |
Information sourced from Uniprot.org
