Anti-CDK2AP2 antibody (51-100 aa) (STJ92755)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CDKA2 at the amino acid range 51-100
General Information
| Short Description | Rabbit polyclonal anti-Cyclin-dependent kinase 2-associated protein 2 (51-100 aa) for use in IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDK2AP2 |
| Gene ID | 10263 |
| Uniprot ID | CDKA2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CDKA2 at the amino acid range 51-100 |
| Immunogen Region | 51-100 aa |
| Specificity | DOC-1R Polyclonal Antibody detects endogenous levels of DOC-1R protein. |
Additional Info
| Post Translational Modifications | Phosphorylated by MAPK1 and CDK2. |
| Function | Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation.represses CDK2 activation by inhibiting its interaction with cyclin E and A. Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes. |
| Protein Name | Cyclin-Dependent Kinase 2-Associated Protein 2Cdk2-Associated Protein 2Doc-1-Related ProteinDoc-1r |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusAccumulates In Immature Oocytes In The NucleusDuring The First Meiotic DivisionAccumulates In The Cytoplasm And Localizes In Dots In The Vicinity Of The Chromosomes In A Region Enriched In Microtubules |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase 2-Associated Protein 2 antibodyAnti-Cdk2-Associated Protein 2 antibodyAnti-Doc-1-Related Protein antibodyAnti-Doc-1r antibodyAnti-CDK2AP2 antibodyAnti-DOC1R antibody |
Information sourced from Uniprot.org