• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-CDC42SE2 antibody (3-53 aa) (STJ196184)

SKU:
STJ196184

€57.50 - €282.50
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CDC42 small effector protein 2 (3-53 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDC42SE2
Gene ID: 56990
Uniprot ID: C42S2_HUMAN
Immunogen Region: 3-53 aa
Specificity: This antibody detects endogenous levels of C42S2 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human C42S2 at the amino acid range 3-53
Function Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
Protein Name Cdc42 Small Effector Protein 2
Small Effector Of Cdc42 Protein 2
Database Links Reactome: R-HSA-9013148
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Membrane
Lipid-Anchor
Cell Projection
Phagocytic Cup
Recruited To The Activated Tcr Prior Actin Polymerization
Localizes At The Phagocytic Cup Of Macrophages
Alternative Antibody Names Anti-Cdc42 Small Effector Protein 2 antibody
Anti-Small Effector Of Cdc42 Protein 2 antibody
Anti-CDC42SE2 antibody
Anti-SPEC2 antibody

Information sourced from Uniprot.org

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