| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CDC42EP3 (1-254) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CDC42EP3 |
| Gene ID: |
10602 |
| Uniprot ID: |
BORG2_HUMAN |
| Immunogen Region: |
1-254 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human CDC42EP3 (NP_006440.2). |
| Immunogen Sequence: |
MPAKTPIYLKAANNKKGKKF KLRDILSPDMISPPLGDFRH TIHIGKEGQHDVFGDISFLQ GNYELLPGNQEKAHLGQFPG HNEFFRANSTSDSVFTETPS PVLKNAISLPTIGGSQALML PLLSPVTFNSKQESFGPAKL PRLSCEPVMEEKAQEKSSLL ENGTVHQGDTSWGSSGSASQ SSQGRDSHSSSLSEQYPDWP AEDMFDHPTPCELIKGKTKS EESLSDLTGSLLSLQLDLG |
| Tissue Specificity | Highly expressed in the heart and weakly in the brain. |
| Function | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. |
| Protein Name | Cdc42 Effector Protein 3Binder Of Rho Gtpases 2Mse55-Related Cdc42-Binding Protein |
| Database Links | Reactome: R-HSA-5687128Reactome: R-HSA-9013148Reactome: R-HSA-9013406 |
| Cellular Localisation | Endomembrane SystemPeripheral Membrane ProteinCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Cdc42 Effector Protein 3 antibodyAnti-Binder Of Rho Gtpases 2 antibodyAnti-Mse55-Related Cdc42-Binding Protein antibodyAnti-CDC42EP3 antibodyAnti-BORG2 antibodyAnti-CEP3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
