Anti-CDC42EP3 antibody (1-254) (STJ110778)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CDC42EP3 (1-254) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDC42EP3 |
| Gene ID | 10602 |
| Uniprot ID | BORG2_HUMAN |
| Immunogen Region | 1-254 |
| Immunogen Sequence | MPAKTPIYLKAANNKKGKKF KLRDILSPDMISPPLGDFRH TIHIGKEGQHDVFGDISFLQ GNYELLPGNQEKAHLGQFPG HNEFFRANSTSDSVFTETPS PVLKNAISLPTIGGSQALML PLLSPVTFNSKQESFGPAKL PRLSCEPVMEEKAQEKSSLL ENGTVHQGDTSWGSSGSASQ SSQGRDSHSSSLSEQYPDWP AEDMFDHPTPCELIKGKTKS EESLSDLTGSLLSLQLDLG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human CDC42EP3 (NP_006440.2). |
Additional Info
| Tissue Specificity | Highly expressed in the heart and weakly in the brain. |
| Function | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. |
| Protein Name | Cdc42 Effector Protein 3Binder Of Rho Gtpases 2Mse55-Related Cdc42-Binding Protein |
| Database Links | Reactome: R-HSA-5687128Reactome: R-HSA-9013148Reactome: R-HSA-9013406 |
| Cellular Localisation | Endomembrane SystemPeripheral Membrane ProteinCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Cdc42 Effector Protein 3 antibodyAnti-Binder Of Rho Gtpases 2 antibodyAnti-Mse55-Related Cdc42-Binding Protein antibodyAnti-CDC42EP3 antibodyAnti-BORG2 antibodyAnti-CEP3 antibody |
Information sourced from Uniprot.org