Anti-CD88/C5AR1 antibody [SAA0039] {PerCP} (STJA0030250)
SPECIFICATIONS
ClonalityMonoclonal
HostHuman
ConjugationPerCP
IsotypeIgG1k
General Information
| Short Description | Human monoclonal C5a Anaphylatoxin Chemotactic Receptor 1 antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Human |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0039 |
| Isotype | IgG1k |
| Conjugation | PerCP |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months. Protect from light. Do not freeze. |
Target Information
| Gene Symbol | C5AR1 |
| Gene ID | 728 |
| Uniprot ID | C5AR1_HUMAN |
Additional Info
| Function | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. |
| Protein Name | C5a Anaphylatoxin Chemotactic Receptor 1C5a Anaphylatoxin Chemotactic ReceptorC5a-RC5arCd Antigen Cd88 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594Reactome: R-HSA-6798695Reactome: R-HSA-977606 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmic VesiclePhosphorylated C5ar Colocalizes With Arrb1 And Arrb2 In Cytoplasmic Vesicles |
| Alternative Antibody Names | Anti-C5a Anaphylatoxin Chemotactic Receptor 1 antibodyAnti-C5a Anaphylatoxin Chemotactic Receptor antibodyAnti-C5a-R antibodyAnti-C5ar antibodyAnti-Cd Antigen Cd88 antibodyAnti-C5AR1 antibodyAnti-C5AR antibodyAnti-C5R1 antibody |
Information sourced from Uniprot.org