Anti-CD88/C5AR1 antibody [SAA0039] {PerCP} (STJA0030250)

SPECIFICATIONS
ClonalityMonoclonal
HostHuman
ConjugationPerCP
IsotypeIgG1k
STJA0030250-100
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General Information

Short DescriptionHuman monoclonal C5a Anaphylatoxin Chemotactic Receptor 1 antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsFC
HostHuman
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSAA0039
IsotypeIgG1k
ConjugationPerCP
Concentration0.5 mg/mL
PurificationPurified
FormulationPBS pH 7.4, 50% glycerol, 0.05% proclin300
Storage InstructionStore at 4°C for 12 months. Protect from light. Do not freeze.

Target Information

Gene SymbolC5AR1
Gene ID728
Uniprot IDC5AR1_HUMAN

Additional Info

Function Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
Protein Name C5a Anaphylatoxin Chemotactic Receptor 1
C5a Anaphylatoxin Chemotactic Receptor
C5a-R
C5ar
Cd Antigen Cd88
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-418594
Reactome: R-HSA-6798695
Reactome: R-HSA-977606
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle
Phosphorylated C5ar Colocalizes With Arrb1 And Arrb2 In Cytoplasmic Vesicles
Alternative Antibody Names Anti-C5a Anaphylatoxin Chemotactic Receptor 1 antibody
Anti-C5a Anaphylatoxin Chemotactic Receptor antibody
Anti-C5a-R antibody
Anti-C5ar antibody
Anti-Cd Antigen Cd88 antibody
Anti-C5AR1 antibody
Anti-C5AR antibody
Anti-C5R1 antibody

Information sourced from Uniprot.org

Citations

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