• Formalin-fixed, paraffin-embedded human tonsil stained with anti-CD205 antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of dendritic cells

Anti-CD205 antibody (1006-1130aa) [ZM360] (STJ180557)

SKU:
STJ180557

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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD205 (1006-1130aa) is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: ZM360
Conjugation: Unconjugated
Isotype: IgG2b/Kappa
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100-200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol: LY75
Gene ID: 100526664/4065
Uniprot ID: LY75_HUMAN
Immunogen Region: 1006-1130aa
Specificity: Positive Control: Tonsil
Immunogen: Recombinant fragment (around aa1006-1130) of human LY75 protein
Tissue Specificity Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
Post Translational Modifications N-glycosylated.
Function Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B-lymphocytes.
Protein Name Lymphocyte Antigen 75
Ly-75
C-Type Lectin Domain Family 13 Member B
Dec-205
Gp200-Mr6
Cd Antigen Cd205
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Lymphocyte Antigen 75 antibody
Anti-Ly-75 antibody
Anti-C-Type Lectin Domain Family 13 Member B antibody
Anti-Dec-205 antibody
Anti-Gp200-Mr6 antibody
Anti-Cd Antigen Cd205 antibody
Anti-LY75 antibody
Anti-CD205 antibody
Anti-CLEC13B antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance