| Host: |
Mouse |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-CD205 (1006-1130aa) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
ZM360 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2b/Kappa |
| Formulation: |
Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: |
Affinity purified |
| Dilution Range: |
1:100-200 |
| Storage Instruction: |
Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: |
LY75 |
| Gene ID: |
100526664/4065 |
| Uniprot ID: |
LY75_HUMAN |
| Immunogen Region: |
1006-1130aa |
| Specificity: |
Positive Control: Tonsil |
| Immunogen: |
Recombinant fragment (around aa1006-1130) of human LY75 protein |
| Tissue Specificity | Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells. |
| Post Translational Modifications | N-glycosylated. |
| Function | Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B-lymphocytes. |
| Protein Name | Lymphocyte Antigen 75Ly-75C-Type Lectin Domain Family 13 Member BDec-205Gp200-Mr6Cd Antigen Cd205 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Lymphocyte Antigen 75 antibodyAnti-Ly-75 antibodyAnti-C-Type Lectin Domain Family 13 Member B antibodyAnti-Dec-205 antibodyAnti-Gp200-Mr6 antibodyAnti-Cd Antigen Cd205 antibodyAnti-LY75 antibodyAnti-CD205 antibodyAnti-CLEC13B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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