Anti-CD20/MS4A1 antibody (C-Term) (STJ70052)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CD20/MS4A1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 35kDa band observed in Human Lymph lysates (calculated MW of 33.1kDa according to NP_068769.2). Recommended concentration: 0.003-0.01µg/ml. Primary incubation was 1 hour.IHC |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | MS4A1 |
| Gene ID | 931 |
| Uniprot ID | CD20_HUMAN |
| Accession Number | NP_068769.2; NP_690605.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | CQDQESSPIENDSSP |
| Specificity | Please note that both reported variants (NP_068769.2 and NP_690605.1) encode the same protein. |
Additional Info
| Post Translational Modifications | Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate. |
| Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
| Protein Name | B-Lymphocyte Antigen Cd20B-Lymphocyte Surface Antigen B1Bp35Leukocyte Surface Antigen Leu-16Membrane-Spanning 4-Domains Subfamily A Member 1Cd Antigen Cd20 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLipid-AnchorConstitutively Associated With Membrane Rafts |
| Alternative Antibody Names | Anti-B-Lymphocyte Antigen Cd20 antibodyAnti-B-Lymphocyte Surface Antigen B1 antibodyAnti-Bp35 antibodyAnti-Leukocyte Surface Antigen Leu-16 antibodyAnti-Membrane-Spanning 4-Domains Subfamily A Member 1 antibodyAnti-Cd Antigen Cd20 antibodyAnti-MS4A1 antibodyAnti-CD20 antibody |
Information sourced from Uniprot.org