Anti-CD2 antibody (235-351) (STJ117816)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CD2 (235-351) antibody for use in WB, IHC-P and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CD2 |
| Gene ID | 914 |
| Uniprot ID | CD2_HUMAN |
| Immunogen Region | 235-351 |
| Immunogen Sequence | TKRKKQRSRRNDEELETRAH RVATEERGRKPHQIPASTPQ NPATSQHPPPPPGHRSQAPS HRPPPPGHRVQHQPQKRPPA PSGTQVHQQKGPPLPRPRVQ PKPPHGAAENSLSPSSN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 235-351 of human CD2 (NP_001758.2). |
Additional Info
| Tissue Specificity | Expressed in natural killer cells (at protein level). |
| Function | CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. |
| Protein Name | T-Cell Surface Antigen Cd2Erythrocyte ReceptorLfa-2Lfa-3 ReceptorRosette ReceptorT-Cell Surface Antigen T11/Leu-5Cd Antigen Cd2 |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell Surface Antigen Cd2 antibodyAnti-Erythrocyte Receptor antibodyAnti-Lfa-2 antibodyAnti-Lfa-3 Receptor antibodyAnti-Rosette Receptor antibodyAnti-T-Cell Surface Antigen T11/Leu-5 antibodyAnti-Cd Antigen Cd2 antibodyAnti-CD2 antibodyAnti-SRBC antibody |
Information sourced from Uniprot.org