| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-T-cell surface glycoprotein CD1e, membrane-associated (217-266 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CD1E |
| Gene ID: | 913 |
| Uniprot ID: | CD1E_HUMAN |
| Immunogen Region: | 217-266 aa |
| Specificity: | CD1e Polyclonal Antibody detects endogenous levels of CD1e protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CD1E at the amino acid range 217-266 |
| Post Translational Modifications | Mono-ubiquitinated. Proteolytically cleaved in late endosomes to yield a soluble form. |
| Function | T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active. |
| Protein Name | T-Cell Surface Glycoprotein Cd1e - Membrane-Associated Hcd1e R2g1 Cd Antigen Cd1e Cleaved Into - T-Cell Surface Glycoprotein Cd1e - Soluble Scd1e |
| Cellular Localisation | T-Cell Surface Glycoprotein Cd1e Membrane-Associated: Golgi Apparatus Membrane Single-Pass Type I Membrane Protein Early Endosome Late Endosome Predominantly Localized In The Trans-Golgi Network In Immature Dendritic Cells And As A Cleaved Soluble Protein In The Lysosome Lumen Of Mature Dendritic Cells Soluble: Lysosome Lumen |
| Alternative Antibody Names | Anti-T-Cell Surface Glycoprotein Cd1e - Membrane-Associated antibody Anti-Hcd1e antibody Anti-R2g1 antibody Anti-Cd Antigen Cd1e Cleaved Into - T-Cell Surface Glycoprotein Cd1e - Soluble antibody Anti-Scd1e antibody Anti-CD1E antibody |
Information sourced from Uniprot.org