Anti-CD1E antibody (217-266 aa) (STJ92101)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CD1E at the amino acid range 217-266
General Information
| Short Description | Rabbit polyclonal anti-T-cell surface glycoprotein CD1e, membrane-associated (217-266 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CD1E |
| Gene ID | 913 |
| Uniprot ID | CD1E_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CD1E at the amino acid range 217-266 |
| Immunogen Region | 217-266 aa |
| Specificity | CD1e Polyclonal Antibody detects endogenous levels of CD1e protein. |
Additional Info
| Post Translational Modifications | Mono-ubiquitinated. Proteolytically cleaved in late endosomes to yield a soluble form. |
| Function | T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active. |
| Protein Name | T-Cell Surface Glycoprotein Cd1e - Membrane-AssociatedHcd1eR2g1Cd Antigen Cd1e Cleaved Into - T-Cell Surface Glycoprotein Cd1e - SolubleScd1e |
| Database Links | |
| Cellular Localisation | T-Cell Surface Glycoprotein Cd1eMembrane-Associated: Golgi Apparatus MembraneSingle-Pass Type I Membrane ProteinEarly EndosomeLate EndosomePredominantly Localized In The Trans-Golgi Network In Immature Dendritic CellsAnd As A CleavedSoluble Protein In The Lysosome Lumen Of Mature Dendritic CellsSoluble: Lysosome Lumen |
| Alternative Antibody Names | Anti-T-Cell Surface Glycoprotein Cd1e - Membrane-Associated antibodyAnti-Hcd1e antibodyAnti-R2g1 antibodyAnti-Cd Antigen Cd1e Cleaved Into - T-Cell Surface Glycoprotein Cd1e - Soluble antibodyAnti-Scd1e antibodyAnti-CD1E antibody |
Information sourced from Uniprot.org