| Host: |
Armenian Hamster |
| Applications: |
FC/Block |
| Reactivity: |
Mouse |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Armenian Hamster monoclonal antibody anti-C-X-C chemokine receptor type 3 is suitable for use in Flow Cytometry and Universal research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
CXCR3-173 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.2 µm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as determined by LAL gel clotting assay. |
| Concentration: |
0.5 mg/mL |
| Storage Instruction: |
Store at 2-8°C. Do not freeze this product. |
| Tissue Specificity | Expresses in lymphoid organs and Th1 cells. |
| Post Translational Modifications | Sulfation on Tyr-27 and Tyr-29 is essential for CXCL10 binding. N-glycosylated. |
| Function | Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response. Binds to CCL21. |
| Protein Name | C-X-C Chemokine Receptor Type 3Cxc-R3Cxcr-3Interferon-Inducible Protein 10 ReceptorIp-10 ReceptorCd Antigen Cd183 |
| Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-X-C Chemokine Receptor Type 3 antibodyAnti-Cxc-R3 antibodyAnti-Cxcr-3 antibodyAnti-Interferon-Inducible Protein 10 Receptor antibodyAnti-Ip-10 Receptor antibodyAnti-Cd Antigen Cd183 antibodyAnti-Cxcr3 antibodyAnti-Cmkar3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Anti-CD183/Cxcr3 antibody [CXCR3-173] {AF647} (STJA0001731)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/147515/292794/STJA0001731_1__09092.1631206761.jpg?c=1 "Anti-CD183/Cxcr3 antibody [CXCR3-173] {AF647} (STJA0001731)")
![C57BL/6 murine splenocytes were stained with Anti-CD183/CXCR3 antibody (STJA0000686) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained splenocytes (empty black histogram) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/145539/292197/STJA0000686_1__76341.1631206041.jpg?c=1 "C57BL/6 murine splenocytes were stained with Anti-CD183/CXCR3 antibody (STJA0000686) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained splenocytes (empty black histogram) were used as control.")