Anti-CD183/Cxcr3 antibody [CXCR3-173] (STJA0001725)

SKU:
STJA0001725

Current Stock:
Host: Armenian Hamster
Applications: FC/Block
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Armenian Hamster monoclonal antibody anti-C-X-C chemokine receptor type 3 is suitable for use in Flow Cytometry and Universal research applications.
Clonality: Monoclonal
Clone ID: CXCR3-173
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.2 µm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as determined by LAL gel clotting assay.
Concentration: 0.5 mg/mL
Storage Instruction: Store at 2-8°C. Do not freeze this product.
Gene Symbol: Cxcr3
Gene ID: 12766
Uniprot ID: CXCR3_MOUSE
Tissue Specificity Expresses in lymphoid organs and Th1 cells.
Post Translational Modifications Sulfation on Tyr-27 and Tyr-29 is essential for CXCL10 binding. N-glycosylated.
Function Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response. Binds to CCL21.
Protein Name C-X-C Chemokine Receptor Type 3
Cxc-R3
Cxcr-3
Interferon-Inducible Protein 10 Receptor
Ip-10 Receptor
Cd Antigen Cd183
Database Links Reactome: R-MMU-380108
Reactome: -MMU-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-C-X-C Chemokine Receptor Type 3 antibody
Anti-Cxc-R3 antibody
Anti-Cxcr-3 antibody
Anti-Interferon-Inducible Protein 10 Receptor antibody
Anti-Ip-10 Receptor antibody
Anti-Cd Antigen Cd183 antibody
Anti-Cxcr3 antibody
Anti-Cmkar3 antibody

Information sourced from Uniprot.org

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