Anti-CD147 antibody [CB43] (STJ16100155)

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STJ16100155-100
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Short Description :Mouse monoclonal anti-CD147 for use in FC, IHC-F and IF in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC/IHC-F/IF
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :CB43
Isotype:IgM
Conjugation:Unconjugated
Concentration:100 Mu g/mL
Formulation:PBS with 0.02% sodium azide
Storage Instruction:Store at 2-8°C for up to 1-year, upon receipt.
Immunogen:Native leucocytes
Background CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.

Information sourced from Uniprot.org