Anti-CD147 antibody [CB43] (STJ16100155)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgM
ImmunogenNative leucocytes
STJ16100155-100
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General Information

Short DescriptionMouse monoclonal anti-CD147 for use in FC, IHC-F and IF in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsFC/IHC-F/IF
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDCB43
IsotypeIgM
ConjugationUnconjugated
Concentration100 Mu g/mL
FormulationPBS with 0.02% sodium azide
Storage InstructionStore at 2-8ยฐC for up to 1-year, upon receipt.

Target Information

ImmunogenNative leucocytes

Additional Info

Background CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.

Information sourced from Uniprot.org

Citations

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