Anti-CD147 antibody [CB43] (STJ16100155)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgM
ImmunogenNative leucocytes
General Information
| Short Description | Mouse monoclonal anti-CD147 for use in FC, IHC-F and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IHC-F/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | CB43 |
| Isotype | IgM |
| Conjugation | Unconjugated |
| Concentration | 100 Mu g/mL |
| Formulation | PBS with 0.02% sodium azide |
| Storage Instruction | Store at 2-8ยฐC for up to 1-year, upon receipt. |
Target Information
| Immunogen | Native leucocytes |
Additional Info
| Background | CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis. |
Information sourced from Uniprot.org