![Anti-CD11c antibody [5D11] (STJ16100447)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149164/346789/STJ16100447_1__28004.1681998891.jpg?c=1 "Anti-CD11c antibody [5D11] (STJ16100447)")
![Anti-CD11c antibody [5D11] (STJ16100447)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149164/346789/STJ16100447_1__28004.1681998891.jpg?c=1 "Anti-CD11c antibody [5D11] (STJ16100447)")
Anti-CD11c antibody [5D11] (STJ16100447)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal anti-CD11c for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 5D11 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Dilution Range | IHC 1:20 – 1:80 |
| Formulation | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | ITGAX |
| Gene ID | 3687 |
| Uniprot ID | ITAX_HUMAN |
Additional Info
| Tissue Specificity | Predominantly expressed in monocytes and granulocytes. |
| Function | Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. |
| Protein Name | Integrin Alpha-XCd11 Antigen-Like Family Member CLeu M5Leukocyte Adhesion Glycoprotein P150 -95 Alpha ChainLeukocyte Adhesion Receptor P150 -95Cd Antigen Cd11c |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-216083Reactome: R-HSA-3000178Reactome: R-HSA-6785807Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-X antibodyAnti-Cd11 Antigen-Like Family Member C antibodyAnti-Leu M5 antibodyAnti-Leukocyte Adhesion Glycoprotein P150 -95 Alpha Chain antibodyAnti-Leukocyte Adhesion Receptor P150 -95 antibodyAnti-Cd Antigen Cd11c antibodyAnti-ITGAX antibodyAnti-CD11C antibody |
Information sourced from Uniprot.org