Anti-CD11c antibody [5D11] (STJ16100447)

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STJ16100447
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Short Description :Mouse monoclonal anti-CD11c for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :5D11
Isotype:IgG2a
Conjugation:Unconjugated
Dilution Range:IHC 1:20 – 1:80
Formulation:Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Storage Instruction:Store at 2-8°C for up to 1-year, upon receipt.
Gene Symbol:ITGAX
Gene ID:3687
Uniprot ID:ITAX_HUMAN
Tissue Specificity Predominantly expressed in monocytes and granulocytes.
Function Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Protein Name Integrin Alpha-X
Cd11 Antigen-Like Family Member C
Leu M5
Leukocyte Adhesion Glycoprotein P150 -95 Alpha Chain
Leukocyte Adhesion Receptor P150 -95
Cd Antigen Cd11c
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-216083
Reactome: R-HSA-3000178
Reactome: R-HSA-6785807
Reactome: R-HSA-6798695
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Integrin Alpha-X antibody
Anti-Cd11 Antigen-Like Family Member C antibody
Anti-Leu M5 antibody
Anti-Leukocyte Adhesion Glycoprotein P150 -95 Alpha Chain antibody
Anti-Leukocyte Adhesion Receptor P150 -95 antibody
Anti-Cd Antigen Cd11c antibody
Anti-ITGAX antibody
Anti-CD11C antibody

Information sourced from Uniprot.org