Anti-CD112/Nectin-2 antibody {ABflo® 488} (STJ11108591)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationABflo® 488
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal CD112/Nectin-2 antibody for use in FC in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | ABflo® 488 |
| Purification | Affinity purification |
| Dilution Range | FC, 5 Mu l per 10^6 cells in 100 Mu l volume |
| Formulation | PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Storage Instruction | Store at 4°C for up to 1 year from the date of receipt. Do not freeze. |
Target Information
| Gene Symbol | Nectin2 |
| Gene ID | 19294 |
| Uniprot ID | NECT2_MOUSE |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Brain, spinal cord, spleen, kidney, heart and liver. |
| Function | Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein. |
| Protein Name | Nectin-2Herpes Virus Entry Mediator BHerpesvirus Entry Mediator BHvebMurine Herpes Virus Entry Protein BMhvebNectin Cell Adhesion Molecule 2Poliovirus Receptor HomologPoliovirus Receptor-Related Protein 2Cd Antigen Cd112 |
| Database Links | Reactome: R-MMU-198933Reactome: -MMU-418990Reactome: -MMU-420597 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Nectin-2 antibodyAnti-Herpes Virus Entry Mediator B antibodyAnti-Herpesvirus Entry Mediator B antibodyAnti-Hveb antibodyAnti-Murine Herpes Virus Entry Protein B antibodyAnti-Mhveb antibodyAnti-Nectin Cell Adhesion Molecule 2 antibodyAnti-Poliovirus Receptor Homolog antibodyAnti-Poliovirus Receptor-Related Protein 2 antibodyAnti-Cd Antigen Cd112 antibodyAnti-Nectin2 antibodyAnti-Mph antibodyAnti-Pvr antibodyAnti-Pvrl2 antibodyAnti-Pvs antibody |
Information sourced from Uniprot.org