Anti-CD105 antibody [MEM-226] (STJ16100186)


Current Stock:
Host: Mouse
Applications: FC, IP, WB
Reactivity: Rat, Human
Short Description: Mouse monoclonal antibody anti-CD105 is suitable for use in Flow Cytometry, Immunoprecipitation and Western Blot research applications.
Clonality: Monoclonal
Clone ID: MEM-226
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage Instruction: Store at 2-8°C upon receipt.
Background CD105 (endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.

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12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance