Anti-CCT4 antibody (130-390) (STJ28631)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CCT4 (130-390) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCT4 |
| Gene ID | 10575 |
| Uniprot ID | TCPD_HUMAN |
| Immunogen Region | 130-390 |
| Immunogen Sequence | PTIISESFQKALEKGIEILT DMSRPVELSDRETLLNSATT SLNSKVVSQYSSLLSPMSVN AVMKVIDPATATSVDLRDIK IVKKLGGTIDDCELVEGLVL TQKVSNSGITRVEKAKIGLI QFCLSAPKTDMDNQIVVSDY AQMDRVLREERAYILNLVKQ IKKTGCNVLLIQKSILRDAL SDLALHFLNKMKIMVIKDIE REDIEFICKTIGTKPVAHID QFTADMLGSAELAEEVNLN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 130-390 of human CCT4 (NP_006421.2). |
Additional Info
| Function | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. |
| Protein Name | T-Complex Protein 1 Subunit DeltaTcp-1-DeltaCct-DeltaChaperonin Containing T-Complex Polypeptide 1 Subunit 4Stimulator Of Tar Rna-Binding |
| Database Links | Reactome: R-HSA-389957Reactome: R-HSA-389960Reactome: R-HSA-390450Reactome: R-HSA-390471Reactome: R-HSA-5620922Reactome: R-HSA-6814122 |
| Cellular Localisation | CytoplasmMelanosomeCytoskeletonMicrotubule Organizing CenterCentrosomeCilium Basal BodyIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-T-Complex Protein 1 Subunit Delta antibodyAnti-Tcp-1-Delta antibodyAnti-Cct-Delta antibodyAnti-Chaperonin Containing T-Complex Polypeptide 1 Subunit 4 antibodyAnti-Stimulator Of Tar Rna-Binding antibodyAnti-CCT4 antibodyAnti-CCTD antibodyAnti-SRB antibody |
Information sourced from Uniprot.org