Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-CCT3 (1-300) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CCT3 |
Gene ID: |
7203 |
Uniprot ID: |
TCPG_HUMAN |
Immunogen Region: |
1-300 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CCT3 (NP_005989.3). |
Immunogen Sequence: |
MMGHRPVLVLSQNTKRESGR KVQSGNINAAKTIADIIRTC LGPKSMMKMLLDPMGGIVMT NDGNAILREIQVQHPAAKSM IEISRTQDEEVGDGTTSVII LAGEMLSVAEHFLEQQMHPT VVISAYRKALDDMISTLKKI SIPVDISDSDMMLNIINSSI TTKAISRWSSLACNIALDAV KMVQFEENGRKEIDIKKYAR VEKIPGGIIEDSCVLRGVMI NKDVTHPRMRRYIKNPRIV |
Function | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable). |
Protein Name | T-Complex Protein 1 Subunit GammaTcp-1-GammaCct-GammaHtric5 |
Database Links | Reactome: R-HSA-389957Reactome: R-HSA-389960Reactome: R-HSA-390450Reactome: R-HSA-390471Reactome: R-HSA-5620922Reactome: R-HSA-6814122 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-T-Complex Protein 1 Subunit Gamma antibodyAnti-Tcp-1-Gamma antibodyAnti-Cct-Gamma antibodyAnti-Htric5 antibodyAnti-CCT3 antibodyAnti-CCTG antibodyAnti-TRIC5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance