| Host: |
Rabbit |
| Applications: |
ELISA/IHC/IP/WB |
| Reactivity: |
Human/Monkey |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CCR3 (1-50) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.60-0.70 µg/µl |
| Dilution Range: |
WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:100 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
CCR3 |
| Gene ID: |
1232 |
| Uniprot ID: |
CCR3_HUMAN |
| Immunogen Region: |
1-50 |
| Immunogen: |
Synthetic peptide taken within amino acid region 1-50 on human CCR3 protein. |
| Tissue Specificity | In eosinophils as well as trace amounts in neutrophils and monocytes. |
| Function | Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection. |
| Protein Name | C-C Chemokine Receptor Type 3C C Ckr3C-C Ckr-3Cc-Ckr-3Ccr-3Ccr3Ckr 3Ckr3Eosinophil Eotaxin ReceptorCd Antigen Cd193 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-C Chemokine Receptor Type 3 antibodyAnti-C C Ckr3 antibodyAnti-C-C Ckr-3 antibodyAnti-Cc-Ckr-3 antibodyAnti-Ccr-3 antibodyAnti-Ccr3 antibodyAnti-Ckr 3 antibodyAnti-Ckr3 antibodyAnti-Eosinophil Eotaxin Receptor antibodyAnti-Cd Antigen Cd193 antibodyAnti-CCR3 antibodyAnti-CMKBR3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
