Anti-CCL11 antibody (1-97) (STJ29706)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CCL11 (1-97) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCL11 |
| Gene ID | 6356 |
| Uniprot ID | CCL11_HUMAN |
| Immunogen Region | 1-97 |
| Immunogen Sequence | MKVSAALLWLLLIAAAFSPQ GLAGPASVPTTCCFNLANRK IPLQRLESYRRITSGKCPQK AVIFKTKLAKDICADPKKKW VQDSMKYLDQKSPTPKP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human CCL11 (NP_002977.1). |
Additional Info
| Post Translational Modifications | O-linked glycan consists of a Gal-GalNAc disaccharide which is modified with up to 2 sialic acid residues. |
| Function | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. |
| Protein Name | EotaxinC-C Motif Chemokine 11Eosinophil Chemotactic ProteinSmall-Inducible Cytokine A11 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6785807 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Eotaxin antibodyAnti-C-C Motif Chemokine 11 antibodyAnti-Eosinophil Chemotactic Protein antibodyAnti-Small-Inducible Cytokine A11 antibodyAnti-CCL11 antibodyAnti-SCYA11 antibody |
Information sourced from Uniprot.org