Anti-CCKAR antibody (100-200) (STJ11101179)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CCKAR (100-200) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCKAR |
| Gene ID | 886 |
| Uniprot ID | CCKAR_HUMAN |
| Immunogen Region | 100-200 |
| Immunogen Sequence | IPNLLKDFIFGSAVCKTTTY FMGTSVSVSTFNLVAISLER YGAICKPLQSRVWQTKSHAL KVIAATWCLSFTIMTPYPIY SNLVPFTKNNNQTANMCRFL L |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CCKAR (NP_000721.1). |
Additional Info
| Function | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Protein Name | Cholecystokinin Receptor Type ACck-A ReceptorCck-ArCholecystokinin-1 ReceptorCck1-R |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cholecystokinin Receptor Type A antibodyAnti-Cck-A Receptor antibodyAnti-Cck-Ar antibodyAnti-Cholecystokinin-1 Receptor antibodyAnti-Cck1-R antibodyAnti-CCKAR antibodyAnti-CCKRA antibody |
Information sourced from Uniprot.org