| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CCKAR (100-200) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CCKAR |
| Gene ID: |
886 |
| Uniprot ID: |
CCKAR_HUMAN |
| Immunogen Region: |
100-200 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CCKAR (NP_000721.1). |
| Immunogen Sequence: |
IPNLLKDFIFGSAVCKTTTY FMGTSVSVSTFNLVAISLER YGAICKPLQSRVWQTKSHAL KVIAATWCLSFTIMTPYPIY SNLVPFTKNNNQTANMCRFL L |
| Function | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Protein Name | Cholecystokinin Receptor Type ACck-A ReceptorCck-ArCholecystokinin-1 ReceptorCck1-R |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cholecystokinin Receptor Type A antibodyAnti-Cck-A Receptor antibodyAnti-Cck-Ar antibodyAnti-Cholecystokinin-1 Receptor antibodyAnti-Cck1-R antibodyAnti-CCKAR antibodyAnti-CCKRA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
