| Short Description : | Goat polyclonal antibody anti-CCDC3 (134-148) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications: | Pep-ELISA/WB/IHC |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Dog/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: In transfected HEK293 transiently expressing Human CCDC3 (DYKDDDDK tagged) , a band of approx. 36kDa is observed. No bands are observed in mock-transfected HEK293 and the same band is |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CCDC3 |
| Gene ID: | 83643 |
| Uniprot ID: | CCDC3_HUMAN |
| Accession Number: | NP_113643.1 |
| Immunogen Region: | 134-148 |
| Immunogen Sequence: | PHGVNFQDAIFPDTQ |
| Function | Negatively regulates TNF-alpha-induced pro-inflammatory response in endothelial cells (ECs) via inhibition of TNF-alpha-induced NF-kappaB activation in ECs. Positively regulates lipid accumulation in adipose cells. |
| Protein Name | Coiled-Coil Domain-Containing Protein 3Fat/Vessel-Derived Secretory ProteinFavine |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Coiled-Coil Domain-Containing Protein 3 antibodyAnti-Fat/Vessel-Derived Secretory Protein antibodyAnti-Favine antibodyAnti-CCDC3 antibody |
Information sourced from Uniprot.org
![Immunohistochemistry analysis of EDF1 in paraffin-embedded mouse lung using [KO Validated] EDF1 Rabbit polyclonal antibody (STJ23470) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/99544/384668/STJ23470_1__14722.1713153436.jpg?c=1 "Immunohistochemistry analysis of EDF1 in paraffin-embedded mouse lung using [KO Validated] EDF1 Rabbit polyclonal antibody (STJ23470) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.")
