• Immunohistochemistry of human tissue with Anti-ELOVL1 primary antibody (STJ500870) at 1:100 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-ELOVL1 antibody (148-198) (STJ500870)

SKU:
STJ500870-100

£441.50
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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Monkey/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ELOVL1 (148-198) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5 µg/µl
Dilution Range: WB: 1:500
ELISA: 1:10, 000
IP: 1:200
IHC: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ELOVL1
Gene ID: 64834
Uniprot ID: ELOV1_HUMAN
Immunogen Region: 148-198
Immunogen: Synthetic peptide taken within amino acid region 148-198 on human Elongation of very long chain fatty acids protein 1.
Tissue Specificity Ubiquitous.
Function Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Protein Name Elongation Of Very Long Chain Fatty Acids Protein 1
3-Keto Acyl-Coa Synthase Elovl1
Elovl Fatty Acid Elongase 1
Elovl Fa Elongase 1
Very Long Chain 3-Ketoacyl-Coa Synthase 1
Very Long Chain 3-Oxoacyl-Coa Synthase 1
Database Links Reactome: R-HSA-2046105
Reactome: R-HSA-2046106
Reactome: R-HSA-75876
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Elongation Of Very Long Chain Fatty Acids Protein 1 antibody
Anti-3-Keto Acyl-Coa Synthase Elovl1 antibody
Anti-Elovl Fatty Acid Elongase 1 antibody
Anti-Elovl Fa Elongase 1 antibody
Anti-Very Long Chain 3-Ketoacyl-Coa Synthase 1 antibody
Anti-Very Long Chain 3-Oxoacyl-Coa Synthase 1 antibody
Anti-ELOVL1 antibody
Anti-SSC1 antibody
Anti-CGI-88 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance