HEK293 overexpressing Human CCDC3 with C-terminal tag (DYKDDDDK) and probed with anti-DYKDDDDK in the left panel and with STJ72975 (0. 5ug/ml) in the right panel (empty vector transfection in first lanes). Data obtained from Dr. YangXin Fu, Dept Oncology, University of Alberta, Edmonton, Canada.

Anti-CCDC3 antibody (134-148) (STJ72975)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
STJ72975-100
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General Information

Short DescriptionGoat polyclonal antibody anti-CCDC3 (134-148) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
ApplicationsPep-ELISA/WB/IHC
HostGoat
ReactivityHuman/Mouse/Rat/Dog/Pig/Cow
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:64000.
WB: In transfected HEK293 transiently expressing Human CCDC3 (DYKDDDDK tagged) , a band of approx. 36kDa is observed. No bands are observed in mock-transfected HEK293 and the same band is
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20°C on receipt and minimise freeze-thaw cycles.

Target Information

Gene SymbolCCDC3
Gene ID83643
Uniprot IDCCDC3_HUMAN
Accession NumberNP_113643.1
Immunogen Region134-148
Immunogen SequencePHGVNFQDAIFPDTQ

Additional Info

Function Negatively regulates TNF-alpha-induced pro-inflammatory response in endothelial cells (ECs) via inhibition of TNF-alpha-induced NF-kappaB activation in ECs. Positively regulates lipid accumulation in adipose cells.
Protein Name Coiled-Coil Domain-Containing Protein 3
Fat/Vessel-Derived Secretory Protein
Favine
Cellular Localisation Secreted
Alternative Antibody Names Anti-Coiled-Coil Domain-Containing Protein 3 antibody
Anti-Fat/Vessel-Derived Secretory Protein antibody
Anti-Favine antibody
Anti-CCDC3 antibody

Information sourced from Uniprot.org

Citations

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