Anti-MAGOHB antibody (1-148) (STJ118632)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MAGOHB (1-148) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAGOHB |
| Gene ID | 55110 |
| Uniprot ID | MGN2_HUMAN |
| Immunogen Region | 1-148 |
| Immunogen Sequence | MAVASDFYLRYYVGHKGKFG HEFLEFEFRPDGKLRYANNS NYKNDVMIRKEAYVHKSVME ELKRIIDDSEITKEDDALWP PPDRVGRQELEIVIGDEHIS FTTSKIGSLIDVNQSKDPEG LRVFYYLVQDLKCLVFSLIG LHFKIKPI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-148 of human MAGOHB (NP_060518.1). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | Required for pre-mRNA splicing as component of the spliceosome. Plays a redundant role with MAGOH in the exon junction complex and in the nonsense-mediated decay (NMD) pathway. |
| Protein Name | Protein Mago Nashi Homolog 2 |
| Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72187Reactome: R-HSA-73856Reactome: R-HSA-9010553Reactome: R-HSA-975957 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein Mago Nashi Homolog 2 antibodyAnti-MAGOHB antibodyAnti-MAGOH2 antibody |
Information sourced from Uniprot.org