Anti-CCBL1 antibody (1-270) (STJ28625)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CCBL1 (1-270) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:10-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KYAT1 |
| Gene ID | 883 |
| Uniprot ID | KAT1_HUMAN |
| Immunogen Region | 1-270 |
| Immunogen Sequence | MAKQLQARRLDGIDYNPWVE FVKLASEHDVVNLGQGFPDF PPPDFAVEAFQHAVSGDFML NQYTKTFVIIIEPFFDCYEP MTMMAGGRPVFVSLKPGPIQ NGELGSSSNWQLDPMELAGK FTSRTKALVLNTPNNPLGKV FSREELELVASLCQQHDVVC ITDEVYQWMVYDGHQHISIA SLPGMWERTLTIGSAGKTFS ATGWKVGWVLGPDHIMKHLR TVHQNSVFHCPTQSQAAVA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CCBL1 (NP_001116144.1). |
Additional Info
| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. |
| Protein Name | Kynurenine--Oxoglutarate Transaminase 1Cysteine-S-Conjugate Beta-LyaseGlutamine Transaminase KGtkGlutamine--Phenylpyruvate TransaminaseKynurenine Aminotransferase 1Kynurenine Aminotransferase IKatiKynurenine--Oxoglutarate Transaminase I |
| Database Links | Reactome: R-HSA-71240Reactome: R-HSA-8964208Reactome: R-HSA-8964539 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Kynurenine--Oxoglutarate Transaminase 1 antibodyAnti-Cysteine-S-Conjugate Beta-Lyase antibodyAnti-Glutamine Transaminase K antibodyAnti-Gtk antibodyAnti-Glutamine--Phenylpyruvate Transaminase antibodyAnti-Kynurenine Aminotransferase 1 antibodyAnti-Kynurenine Aminotransferase I antibodyAnti-Kati antibodyAnti-Kynurenine--Oxoglutarate Transaminase I antibodyAnti-KYAT1 antibodyAnti-CCBL1 antibody |
Information sourced from Uniprot.org