| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. |
| Protein Name | Kynurenine--Oxoglutarate Transaminase 1Cysteine-S-Conjugate Beta-LyaseGlutamine Transaminase KGtkGlutamine--Phenylpyruvate TransaminaseKynurenine Aminotransferase 1Kynurenine Aminotransferase IKatiKynurenine--Oxoglutarate Transaminase I |
| Database Links | Reactome: R-HSA-71240Reactome: R-HSA-8964208Reactome: R-HSA-8964539 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Kynurenine--Oxoglutarate Transaminase 1 antibodyAnti-Cysteine-S-Conjugate Beta-Lyase antibodyAnti-Glutamine Transaminase K antibodyAnti-Gtk antibodyAnti-Glutamine--Phenylpyruvate Transaminase antibodyAnti-Kynurenine Aminotransferase 1 antibodyAnti-Kynurenine Aminotransferase I antibodyAnti-Kati antibodyAnti-Kynurenine--Oxoglutarate Transaminase I antibodyAnti-KYAT1 antibodyAnti-CCBL1 antibody |
Information sourced from Uniprot.org
