Anti-CBY1 antibody (2-50 aa) (STJ13100879)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 2-50 of human CBY1 conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-CBY1 (2-50 aa) for use in IHC and WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | CBY1 |
| Gene ID | 25776 |
| Uniprot ID | CBY1_HUMAN |
| Immunogen | A synthetic peptide from aa region 2-50 of human CBY1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | 2-50 aa |
| Specificity | Specific for CBY1. |
Additional Info
| Function | Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. |
| Protein Name | Protein Chibby Homolog 1Arpp-Binding ProteinCytosolic Leucine-Rich ProteinPigea-14Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 |
| Database Links | Reactome: R-HSA-3769402 |
| Cellular Localisation | Nucleus SpeckleCytoplasmCytoskeletonCilium Basal BodyMicrotubule Organizing CenterCentrosomeCentrioleGolgi ApparatusTrans-Golgi NetworkCell ProjectionCiliumFlagellumNucleus |
| Alternative Antibody Names | Anti-Protein Chibby Homolog 1 antibodyAnti-Arpp-Binding Protein antibodyAnti-Cytosolic Leucine-Rich Protein antibodyAnti-Pigea-14 antibodyAnti-Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 antibodyAnti-CBY1 antibodyAnti-ARB1 antibodyAnti-C22orf2 antibodyAnti-CBY antibodyAnti-PGEA1 antibodyAnti-HRIHFB2025 antibody |
Information sourced from Uniprot.org