| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CBY1 (2-50 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
CBY1 |
| Gene ID: |
25776 |
| Uniprot ID: |
CBY1_HUMAN |
| Immunogen Region: |
2-50 aa |
| Specificity: |
Specific for CBY1. |
| Immunogen: |
A synthetic peptide from aa region 2-50 of human CBY1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. |
| Protein Name | Protein Chibby Homolog 1Arpp-Binding ProteinCytosolic Leucine-Rich ProteinPigea-14Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 |
| Database Links | Reactome: R-HSA-3769402 |
| Cellular Localisation | Nucleus SpeckleCytoplasmCytoskeletonCilium Basal BodyMicrotubule Organizing CenterCentrosomeCentrioleGolgi ApparatusTrans-Golgi Network |
| Alternative Antibody Names | Anti-Protein Chibby Homolog 1 antibodyAnti-Arpp-Binding Protein antibodyAnti-Cytosolic Leucine-Rich Protein antibodyAnti-Pigea-14 antibodyAnti-Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 antibodyAnti-CBY1 antibodyAnti-ARB1 antibodyAnti-C22orf2 antibodyAnti-CBY antibodyAnti-PGEA1 antibodyAnti-HRIHFB2025 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
