• Immunohistochemistry analysis of paraffin-embedded mouse testis using CBX8 Antibody (STJ27978) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human colon using CBX8 Antibody (STJ27978) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded rat pancreas using CBX8 Antibody (STJ27978) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of various cell lines, using CBX8 antibody (STJ27978) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-CBX8 antibody (80-280) (STJ27978)

SKU:
STJ27978

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CBX8 (80-280) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CBX8
Gene ID: 57332
Uniprot ID: CBX8_HUMAN
Immunogen Region: 80-280
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-280 of human CBX8 (NP_065700.1).
Immunogen Sequence: LLKAQAKAKAKTYEFRSDSA RGIRIPYPGRSPQDLASTSR AREGLRNMGLSPPASSTSTS STCRAEAPRDRDRDRDRDRE RDRERERERERERERERERE RGTSRVDDKPSSPGDSSKKR GPKPRKELPDPSQRPLGEPS AGLGEYLKGRKLDDTPSGAG KFPAGHSVIQLARRQDSDLV QCGVTSPSSAEATGKLAVDT F
Function Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones.it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Protein Name Chromobox Protein Homolog 8
Polycomb 3 Homolog
Pc3
Hpc3
Rectachrome 1
Database Links Reactome: R-HSA-2559580
Reactome: R-HSA-3108214
Reactome: R-HSA-3899300
Reactome: R-HSA-4551638
Reactome: R-HSA-4570464
Reactome: R-HSA-4655427
Reactome: R-HSA-8939243
Reactome: R-HSA-8943724
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Chromobox Protein Homolog 8 antibody
Anti-Polycomb 3 Homolog antibody
Anti-Pc3 antibody
Anti-Hpc3 antibody
Anti-Rectachrome 1 antibody
Anti-CBX8 antibody
Anti-PC3 antibody
Anti-RC1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance