Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human/Dog/Pig/Cow |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-CBR3 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
ELISA-antibody detection limit dilution 1:32000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
CBR3 |
Gene ID: |
874 |
Uniprot ID: |
CBR3_HUMAN |
Immunogen Region: |
C-Term |
Accession Number: |
NP_001227.1 |
Immunogen Sequence: |
QGQLVHDKVVQNW |
Function | Catalyzes the NADPH-dependent reduction of carbonyl compounds to their corresponding alcohols. Has low NADPH-dependent oxidoreductase activity. Acts on several orthoquinones, acts as well on non-quinone compounds, such as isatin or on the anticancer drug oracin. Best substrates for CBR3 is 1,2- naphthoquinone, hence could play a role in protection against cytotoxicity of exogenous quinones. Exerts activity toward ortho-quinones but not paraquinones. No endogenous substrate for CBR3 except isatin has been identified. |
Protein Name | Carbonyl Reductase Nadph 3Nadph-Dependent Carbonyl Reductase 3Quinone Reductase Cbr3Short Chain Dehydrogenase/Reductase Family 21c Member 2 |
Database Links | Reactome: R-HSA-211945 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Carbonyl Reductase Nadph 3 antibodyAnti-Nadph-Dependent Carbonyl Reductase 3 antibodyAnti-Quinone Reductase Cbr3 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 21c Member 2 antibodyAnti-CBR3 antibodyAnti-SDR21C2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance