• STJ70210 (0. 5µg/ml) staining of HEK293 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-CBR3 antibody (C-Term) (STJ70210)

SKU:
STJ70210-100

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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-CBR3 (C-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: CBR3
Gene ID: 874
Uniprot ID: CBR3_HUMAN
Immunogen Region: C-Term
Accession Number: NP_001227.1
Immunogen Sequence: QGQLVHDKVVQNW
Function Catalyzes the NADPH-dependent reduction of carbonyl compounds to their corresponding alcohols. Has low NADPH-dependent oxidoreductase activity. Acts on several orthoquinones, acts as well on non-quinone compounds, such as isatin or on the anticancer drug oracin. Best substrates for CBR3 is 1,2- naphthoquinone, hence could play a role in protection against cytotoxicity of exogenous quinones. Exerts activity toward ortho-quinones but not paraquinones. No endogenous substrate for CBR3 except isatin has been identified.
Protein Name Carbonyl Reductase Nadph 3
Nadph-Dependent Carbonyl Reductase 3
Quinone Reductase Cbr3
Short Chain Dehydrogenase/Reductase Family 21c Member 2
Database Links Reactome: R-HSA-211945
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Carbonyl Reductase Nadph 3 antibody
Anti-Nadph-Dependent Carbonyl Reductase 3 antibody
Anti-Quinone Reductase Cbr3 antibody
Anti-Short Chain Dehydrogenase/Reductase Family 21c Member 2 antibody
Anti-CBR3 antibody
Anti-SDR21C2 antibody

Information sourced from Uniprot.org

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