| Host: | Rabbit |
| Applications: | IHC-P/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CAST |
| Gene ID: | 831 |
| Uniprot ID: | ICAL_HUMAN |
| Immunogen Region: | 406-695 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 406-695 of human CAST (NP_001177371.1). |
| Immunogen Sequence: | PPEPATLKGTVPDDAVEALA DSLGKKEADPEDGKPVMDKV KEKAKEEDREKLGEKEETIP PDYRLEEVKDKDGKPLLPKE SKEQLPPMSEDFLLDALSED FSGPQNASSLKFEDAKLAAA ISEVVSQTPASTTQAGAPPR DTSQSDKDLDDALDKLSDSL GQRQPDPDENKPMEDKVKEK AKAEHRDKLGERDDTIPPEY RHLLDDNGQDKPVKPPTKKS EDSKKPADDQDPIDALSGD |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue. |
| Protein Name | CalpastatinCalpain InhibitorSperm Bs-17 Component |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-8862803 |
| Alternative Antibody Names | Anti-Calpastatin antibodyAnti-Calpain Inhibitor antibodyAnti-Sperm Bs-17 Component antibodyAnti-CAST antibody |
Information sourced from Uniprot.org
