| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CAST (406-695) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CAST |
| Gene ID: |
831 |
| Uniprot ID: |
ICAL_HUMAN |
| Immunogen Region: |
406-695 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 406-695 of human CAST (NP_001177371.1). |
| Immunogen Sequence: |
PPEPATLKGTVPDDAVEALA DSLGKKEADPEDGKPVMDKV KEKAKEEDREKLGEKEETIP PDYRLEEVKDKDGKPLLPKE SKEQLPPMSEDFLLDALSED FSGPQNASSLKFEDAKLAAA ISEVVSQTPASTTQAGAPPR DTSQSDKDLDDALDKLSDSL GQRQPDPDENKPMEDKVKEK AKAEHRDKLGERDDTIPPEY RHLLDDNGQDKPVKPPTKKS EDSKKPADDQDPIDALSGD |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue. |
| Protein Name | CalpastatinCalpain InhibitorSperm Bs-17 Component |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-8862803 |
| Alternative Antibody Names | Anti-Calpastatin antibodyAnti-Calpain Inhibitor antibodyAnti-Sperm Bs-17 Component antibodyAnti-CAST antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
