Anti-cardiolipin synthase 1 antibody (Internal) (STJ72640)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-cardiolipin synthase 1 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 30kDa band observed in lysates of cell line HEK293 (calculated MW of 32.6kDa according to NP_061968.1). Recommended concentration: 0.2-0.6µg/ml. Primary incubation was 1 hour. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CRLS1 |
| Gene ID | 54675 |
| Uniprot ID | CRLS1_HUMAN |
| Accession Number | NP_061968.1; NP_001120930.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | RSALGSALDPLADK |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_061968.1; NP_001120930.1). |
Additional Info
| Function | Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. |
| Protein Name | Cardiolipin SynthaseCmp-FormingClsProtein Gcd10 Homolog |
| Database Links | Reactome: R-HSA-1482925Reactome: R-HSA-1483076 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cardiolipin Synthase antibodyAnti-Cmp-Forming antibodyAnti-Cls antibodyAnti-Protein Gcd10 Homolog antibodyAnti-CRLS1 antibodyAnti-C20orf155 antibodyAnti-CLS1 antibody |
Information sourced from Uniprot.org