| Tissue Specificity | Expressed exclusively in testis and sperm. Highest expression is found in the neck region of ejaculated sperm with lower levels found in the tail and postacrosome region. |
| Function | F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid. |
| Protein Name | F-Actin-Capping Protein Subunit Alpha-3Capz Alpha-3Cp-Alpha-3Germ Cell-Specific Protein 3 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-3371497Reactome: R-HSA-6807878Reactome: R-HSA-6811436 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-F-Actin-Capping Protein Subunit Alpha-3 antibodyAnti-Capz Alpha-3 antibodyAnti-Cp-Alpha-3 antibodyAnti-Germ Cell-Specific Protein 3 antibodyAnti-CAPZA3 antibodyAnti-CAPAA3 antibodyAnti-GSG3 antibody |
Information sourced from Uniprot.org
