Anti-CAPZA3 antibody (STJA0004680)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human CAPZA3
General Information
| Short Description | Rabbit polyclonal anti-F-Actin-Capping Protein Subunit Alpha-3 for use in IHC and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.9 mg/mL |
| Purification | Affinity purification |
| Dilution Range | IHC 1:50-1:200 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | CAPZA3 |
| Gene ID | 93661 |
| Uniprot ID | CAZA3_HUMAN |
| Immunogen | Recombinant protein of human CAPZA3 |
Additional Info
| Tissue Specificity | Expressed exclusively in testis and sperm. Highest expression is found in the neck region of ejaculated sperm with lower levels found in the tail and postacrosome region. |
| Function | F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid. |
| Protein Name | F-Actin-Capping Protein Subunit Alpha-3Capz Alpha-3Cp-Alpha-3Germ Cell-Specific Protein 3 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-3371497Reactome: R-HSA-6807878Reactome: R-HSA-6811436 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-F-Actin-Capping Protein Subunit Alpha-3 antibodyAnti-Capz Alpha-3 antibodyAnti-Cp-Alpha-3 antibodyAnti-Germ Cell-Specific Protein 3 antibodyAnti-CAPZA3 antibodyAnti-CAPAA3 antibodyAnti-GSG3 antibody |
Information sourced from Uniprot.org