Anti-CAPN10 antibody (1-230) (STJ111907)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CAPN10 (1-230) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAPN10 |
| Gene ID | 11132 |
| Uniprot ID | CAN10_HUMAN |
| Immunogen Region | 1-230 |
| Immunogen Sequence | MRAGRGATPARELFRDAAFP AADSSLFCDLSTPLAQFRED ITWRRPQEICATPRLFPDDP REGQVKQGLLGDCWFLCACA ALQKSRHLLDQVIPPGQPSW ADQEYRGSFTCRIWQFGRWV EVTTDDRLPCLAGRLCFSRC QREDVFWLPLLEKVYAKVHG SYEHLWAGQVADALVDLTGG LAERWNLKGVAGSGGQQDRP GRWEHRTCRQLLHLKDQCLI SCCVLSPRAG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human CAPN10 (NP_075571.1). |
Additional Info
| Tissue Specificity | Detected in primary skeletal muscle cells (at protein level). Ubiquitous. |
| Function | Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. May play a role in insulin-stimulated glucose uptake. |
| Protein Name | Calpain-10Calcium-Activated Neutral Proteinase 10Canp 10 |
| Database Links | Reactome: R-HSA-1474228 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Calpain-10 antibodyAnti-Calcium-Activated Neutral Proteinase 10 antibodyAnti-Canp 10 antibodyAnti-CAPN10 antibodyAnti-KIAA1845 antibody |
Information sourced from Uniprot.org