Anti-CALCA antibody [4901] (STJA0003593)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
Immunogenpurification rat alpha-CGRP.
General Information
| Short Description | Mouse monoclonal anti-CGRP for use in ICC in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ICC |
| Host | Mouse |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 4901 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Purification | This antibody was protein g purified culture from supernatant. |
| Dilution Range | WB not recommendedICC 1:50-1:100 |
| Formulation | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Calca |
| Gene ID | 24241 |
| Uniprot ID | CALCA_RAT |
| Immunogen | purification rat alpha-CGRP. |
Additional Info
| Function | CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex. |
| Protein Name | Calcitonin Gene-Related Peptide 1Cgrp1Alpha-Type CgrpCalcitonin Gene-Related Peptide ICgrp-I |
| Database Links | Reactome: R-RNO-419812 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Calcitonin Gene-Related Peptide 1 antibodyAnti-Cgrp1 antibodyAnti-Alpha-Type Cgrp antibodyAnti-Calcitonin Gene-Related Peptide I antibodyAnti-Cgrp-I antibodyAnti-Calca antibodyAnti-Calc antibody |
Information sourced from Uniprot.org