Immunostaining of CGRP (red) in cryopreserved DRG neurons grown on coverslips. 40xmag. Green staining is PGP9. 5. Yellow staining is the colocalization of CGRP and PGP9. 5. Cells were obtained and photo was provided courtesy of QBMCellScience.

Anti-CALCA antibody [4901] (STJA0003593)

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STJA0003593-100
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Short Description :Mouse monoclonal anti-CGRP for use in ICC in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ICC
Host:Mouse
Reactivity:Human/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :4901
Isotype:IgG2a
Conjugation:Unconjugated
Purification:This antibody was protein g purified culture from supernatant.
Dilution Range:WB not recommended
ICC 1:50-1:100
Formulation:100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:Calca
Gene ID:24241
Uniprot ID:CALCA_RAT
Immunogen:purification rat alpha-CGRP.
Function CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex.
Protein Name Calcitonin Gene-Related Peptide 1
Cgrp1
Alpha-Type Cgrp
Calcitonin Gene-Related Peptide I
Cgrp-I
Database Links
Reactome: R-RNO-419812
Cellular Localisation Secreted
Alternative Antibody Names Anti-Calcitonin Gene-Related Peptide 1 antibody
Anti-Cgrp1 antibody
Anti-Alpha-Type Cgrp antibody
Anti-Calcitonin Gene-Related Peptide I antibody
Anti-Cgrp-I antibody
Anti-Calca antibody
Anti-Calc antibody

Information sourced from Uniprot.org

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