• Western blot of rat synaptic plasma membrane (SPM) lysate showing specific immunolabeling of the ~36 kDa stargazin protein.

Anti-CACNG2 antibody (C-Term) (STJA0003779)

SKU:
STJA0003779-100

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Host: Rabbit
Applications: WB
Reactivity: Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Stargazin (C-Term) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Purification: This antibody was antigen affinity purified from pooled serum.
Dilution Range: WB 1:1000
IHC
ICC
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Cacng2
Gene ID: 12300
Uniprot ID: CCG2_MOUSE
Immunogen Region: C-Term
Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
Tissue Specificity Brain.
Post Translational Modifications Phosphorylation of Thr-321 by PKA impairs interaction with DLG1 and DLG4.
Function Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
Protein Name Voltage-Dependent Calcium Channel Gamma-2 Subunit
Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit
Stargazin
Transmembrane Ampar Regulatory Protein Gamma-2
Tarp Gamma-2
Database Links Reactome: R-MMU-112308
Reactome: -MMU-399719
Reactome: -MMU-5682910
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Synapse
Synaptosome
Alternative Antibody Names Anti-Voltage-Dependent Calcium Channel Gamma-2 Subunit antibody
Anti-Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit antibody
Anti-Stargazin antibody
Anti-Transmembrane Ampar Regulatory Protein Gamma-2 antibody
Anti-Tarp Gamma-2 antibody
Anti-Cacng2 antibody
Anti-Stg antibody

Information sourced from Uniprot.org

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