Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Stargazin (C-Term) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
Purification: |
This antibody was antigen affinity purified from pooled serum. |
Dilution Range: |
WB 1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
Cacng2 |
Gene ID: |
12300 |
Uniprot ID: |
CCG2_MOUSE |
Immunogen Region: |
C-Term |
Immunogen: |
Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. |
Tissue Specificity | Brain. |
Post Translational Modifications | Phosphorylation of Thr-321 by PKA impairs interaction with DLG1 and DLG4. |
Function | Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. |
Protein Name | Voltage-Dependent Calcium Channel Gamma-2 SubunitNeuronal Voltage-Gated Calcium Channel Gamma-2 SubunitStargazinTransmembrane Ampar Regulatory Protein Gamma-2Tarp Gamma-2 |
Database Links | Reactome: R-MMU-112308Reactome: -MMU-399719Reactome: -MMU-5682910 |
Cellular Localisation | MembraneMulti-Pass Membrane ProteinSynapseSynaptosome |
Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Gamma-2 Subunit antibodyAnti-Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit antibodyAnti-Stargazin antibodyAnti-Transmembrane Ampar Regulatory Protein Gamma-2 antibodyAnti-Tarp Gamma-2 antibodyAnti-Cacng2 antibodyAnti-Stg antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance