| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Rat/Mouse/Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CACNB3 (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB. A dilution of 1: 500 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
CACNB3 |
| Gene ID: |
784 |
| Uniprot ID: |
CACB3_HUMAN |
| Immunogen Region: |
C-Term |
| Specificity: |
Specific for CACNB3. |
| Immunogen: |
A synthetic peptide from the c-terminal region of rat CACN conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and shares 90% identity with human sequence. |
| Function | Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation. Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation. |
| Protein Name | Voltage-Dependent L-Type Calcium Channel Subunit Beta-3Cab3Calcium Channel Voltage-Dependent Subunit Beta 3 |
| Database Links | Reactome: R-HSA-112308Reactome: R-HSA-400042Reactome: R-HSA-419037Reactome: R-HSA-422356 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Voltage-Dependent L-Type Calcium Channel Subunit Beta-3 antibodyAnti-Cab3 antibodyAnti-Calcium Channel Voltage-Dependent Subunit Beta 3 antibodyAnti-CACNB3 antibodyAnti-CACNLB3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
